China completed the world’s first CRISPR human test, gene therapy technology has been fully beyond

China completed the world’s first CRISPR human test, gene therapy technology has been fully beyond the United States? According to the latest technology – Sohu "Nature" magazine reported in November 15th, led by Professor Lu uranium in West China Hospital of Sichuan University oncologist’s team has confirmed the CRISPR gene editing cells into a patient with metastatic non-small cell lung cancer. West China Hospital of Sichuan University oncologist Professor Lu Lu uranium uranium in July this year, gene therapy clinical trials by the ethical review board of the West China Hospital, originally planned for human trials in August. First, the team removed the immune cells from the blood of the subjects and knocked out one of the genes by CRISPR-Cas9. The gene is encoded by the PD-1 protein, a protein that normally regulates the cellular immune response, which is used to spread cancer cells. Subsequently, the research team in the laboratory on these gene editing cells were cultured and amplified, and re injected into the patient’s blood, in order to PD-1 role, they can target and kill cancer cells. However, it took longer than expected to expand and grow, and eleven long vacations have slowed the overall progress of the project. Finally, in October 28th, the team completed the first gene editing of cell human injections. There is no doubt that CRISPR technology has caused great changes in the biomedical field, is an epoch-making technology. The technique uses a specific DNA enzyme called CRISPR-Cas9 to search, cut, and replace specific sequences of DNA. This technology can be used in multi fields to imagine, from the change of mouse fur color, to eliminate mosquitoes carrying malaria to breeding insect resistant crops, it can also repair various genetic diseases such as sickle cell anemia in humans. Gene therapy, Chinese has been at the forefront of the world before the CRISPR-Cas9 technology was invented, many researchers have seen the gene editing in the treatment of various diseases in the limitless prospect. However, with the introduction of CRISPR-Cas9 technology, the more simple, efficient and accurate gene editing technology will greatly improve the time of gene therapy in clinical stage. Similar to the United States and the Soviet space race, but this is China and the United States in the field of biological medicine. This competition is important, because the healthy competition will continue to enhance the reliability of technology and terminal products, Carle ·, Professor Zhu said. Carle · June is a pioneer of American tumor cell immunotherapy, is also a major gene therapy research program’s science adviser, the program hopes through the CRISPR technology to mark the three genes in patients’ cells, and finally achieve the purpose of the treatment of various cancers. Carle · Zhu hope that the United States team of researchers in early 2017 to start the first trial treatment. Columbia University professor Carle &m相关的主题文章: